Studies on bacteriocin production by NAG-strains of Vibrio cholerae as a possible epidemiological marker.

201 "non-agglutinable" - i.e. serogroup O:1-negative - Vibrio cholerae strains were tested for bacteriocin production using 14 of the Abbott-shannon standard set of colicin-sensitive strains as indicators. 41.2% of the strains proved to be bacteriocin producers. 29 out of 67 (43%) vibriocin-positive strains originating from one large geographical region gave the same reaction pattern with the applied indicator strains. The possible significance of these vibriocins for epidemiological studies is discussed, and the necessity for further investigations prior to routine bacteriocin typing of O:1-negative V. cholerae strains is pointed out.