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犬弓首蛔虫感染状态与犬体内IgM抗体活性的关系

The IgM antibody activities in relation to the parasitologic status of Toxocara canis in dogs.

作者信息

Matsumura K, Kazuta Y, Endo R, Tanaka K

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1983 Sep;255(2-3):402-5.

PMID:6649984
Abstract

In order to interpret the relation between the IgM antibody activities to Toxocara canis (T. canis) and the parasitologic status, sera from puppies and adult dogs were measured by the enzyme-linked immunosorbent assay. At the same time, autopsy was performed on these dogs for counting the number of T. canis worms and stool examination was carried out for observing the fertilization of eggs. The rates of infection by T. canis in the dogs decreased with age. The number of worms in the intestines ranged one to 39. The IgM antibody activities gradually increased until 3 months of age. Thereafter the significant levels were maintained even at the adult age. However, the IgM antibody levels were not associated with the age and the number of worms (P greater than 0.05) when the correlation coefficients were calculated between them. In contrast to the IgG antibodies, the results of the present study indicated that the IgM antibody activities do not relate to the age, the number of worms and the fertilization of eggs.

摘要

为了解犬弓首蛔虫(T. canis)IgM抗体活性与寄生虫学状态之间的关系,采用酶联免疫吸附试验检测幼犬和成年犬的血清。同时,对这些犬进行尸检以计数犬弓首蛔虫的数量,并进行粪便检查以观察虫卵的受精情况。犬弓首蛔虫在犬中的感染率随年龄增长而降低。肠道内的虫数为1至39条。IgM抗体活性在3月龄前逐渐升高。此后,即使在成年期也维持在显著水平。然而,计算它们之间的相关系数时,IgM抗体水平与年龄和虫数无关(P大于0.05)。与IgG抗体不同,本研究结果表明,IgM抗体活性与年龄、虫数和虫卵受精情况无关。

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