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内源性胃泌素处于不同水平时大鼠小肠内容物的推进与混合情况

Propulsion and mixing of small bowel contents in rat during varied levels of endogenous gastrin.

作者信息

Gustavsson S, Jung B, Lundqvist G, Nilsson F

出版信息

Acta Chir Scand. 1978;144(2):109-14.

PMID:665099
Abstract

The propulsion and mixing of small bowel contents were studied in conscious rats 14 days after antral resection, antral exclusion and gastroentero-anastomosis in order to evaluate the influence of hypo-, hyper- and normogastrinemia, respectively, on the net result of small bowel muscular activities. The quantitative measures of propulsion and mixing did not differ significantly between the groups. There was, however, a significant correlation between high serum gastrin and increased intestinal mixing after antral exclusion and gastroentero-anastomosis. This finding supports earlier studies on gastrin effects on the small bowel obtained by exogenous gastrin infusion.

摘要

为了分别评估低胃泌素血症、高胃泌素血症和正常胃泌素血症对小肠肌肉活动最终结果的影响,研究了在进行胃窦切除、胃窦旷置和胃肠吻合术后14天的清醒大鼠小肠内容物的推进和混合情况。各实验组间推进和混合的定量指标无显著差异。然而,在胃窦旷置和胃肠吻合术后,高血清胃泌素与小肠混合增加之间存在显著相关性。这一发现支持了早期通过外源性注入胃泌素对胃泌素对小肠影响所做的研究。

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1
Propulsion and mixing of small bowel contents in rat during varied levels of endogenous gastrin.内源性胃泌素处于不同水平时大鼠小肠内容物的推进与混合情况
Acta Chir Scand. 1978;144(2):109-14.
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Propulsion and mixing of small bowel contents during exogenous gastrin infusion. An experimental study in rat.
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