[伴有三种抗红细胞自身抗体的自身免疫性溶血性贫血]
[Autoimmune hemolytic anemia with presence of 3 types of autoantibodies to erythrocytes].
作者信息
Seyfriedowa H, Bragiel I, Górska B, Zupańska B
出版信息
Acta Haematol Pol. 1978 Jan-Mar;9(1):45-50.
PMID:665127
Abstract
In a patient with chronic lymphatic leukaemia severe autoimmunohaemolytic anaemia (NAIH) was observed with coexistence of cold incomplete IgM, warm incomplete IgG and warm haemolysins active against papainized erythrocytes in low pH medium. The serologic and immunochemical characteristics of autoantibodies are presented and the mechanism of their action in vitro is tentatively explained.
摘要
在一名慢性淋巴细胞白血病患者中，观察到严重的自身免疫性溶血性贫血（NAIH），同时存在冷反应性不完全IgM、温反应性不完全IgG以及在低pH介质中对木瓜蛋白酶处理的红细胞具有活性的温溶血素。本文介绍了自身抗体的血清学和免疫化学特征，并初步解释了它们在体外的作用机制。
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