伴有温性和冷性红细胞自身抗体及温性溶血素并存的自身免疫性溶血性贫血

Autoimmune hemolytic anemia with concurrence of warm and cold red cell autoantibodies and a warm hemolysin.

作者信息

Freedman J, Lim F C, Musclow E, Fernandes B, Rother I

出版信息

Transfusion. 1985 Jul-Aug;25(4):368-72. doi: 10.1046/j.1537-2995.1985.25485273819.x.

DOI:10.1046/j.1537-2995.1985.25485273819.x

Abstract

This report describes the laboratory findings and clinical course of a patient with thrombophlebitis, venous gangrene, and autoimmune hemolytic anemia. Three concomitant red cell autoantibody activities were detected: a low-titer, high-thermal-amplitude, IgM anti-I cold agglutinin; an IgG warm 'incomplete' panagglutinating autoantibody; and an IgM warm hemolysin.

摘要

本报告描述了一名患有血栓性静脉炎、静脉坏疽和自身免疫性溶血性贫血患者的实验室检查结果及临床病程。检测到三种同时存在的红细胞自身抗体活性：一种低滴度、高热幅度的IgM抗-I冷凝集素；一种IgG温性“不完全”全凝集自身抗体；以及一种IgM温性溶血素。