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DBA/2W小鼠中的品系特异性可移植性髓样癌。

Strain specific transplantable medullar carcinoma in DBA/2W mice.

作者信息

Włodarski K, Mazur S

出版信息

Arch Immunol Ther Exp (Warsz). 1983;31(2):255-60.

PMID:6651482
Abstract

A solid medullar carcinoma, which arose spontaneously in DBA/2W mouse was passed in vivo in syngeneic and semisyngeneic recipients for ten generations without alteration of its morphology. This cancer, which we named WAMIB, has a relatively slow growth ratio with MST 59 days and can be easily reproduced from cell cultures and/or from cryopreserved tumor fragments. WAMIB tumor is nearly diploid and does not metastasize, does not regress spontaneously and is rejected when grafted into allogeneic recipient animals.

摘要

一种在DBA/2W小鼠体内自发产生的实体髓样癌,在同基因和半同基因受体动物体内连续传代十代,其形态未发生改变。我们将这种癌症命名为WAMIB,它的生长速度相对较慢,平均生存时间为59天,并且能够很容易地从细胞培养物和/或冷冻保存的肿瘤片段中再次培育出来。WAMIB肿瘤几乎是二倍体,不发生转移,不会自发消退,移植到异基因受体动物体内时会被排斥。

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Strain specific transplantable medullar carcinoma in DBA/2W mice.DBA/2W小鼠中的品系特异性可移植性髓样癌。
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