Strain specific transplantable medullar carcinoma in DBA/2W mice.

A solid medullar carcinoma, which arose spontaneously in DBA/2W mouse was passed in vivo in syngeneic and semisyngeneic recipients for ten generations without alteration of its morphology. This cancer, which we named WAMIB, has a relatively slow growth ratio with MST 59 days and can be easily reproduced from cell cultures and/or from cryopreserved tumor fragments. WAMIB tumor is nearly diploid and does not metastasize, does not regress spontaneously and is rejected when grafted into allogeneic recipient animals.