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正常人体胃黏液中多糖的存在。

The presence of polysaccharide in normal human gastric mucus.

作者信息

Clamp J R, Cooper B, Creeth J M, Ene D, Barrett J, Gough M

出版信息

Biochem J. 1983 Nov 1;215(2):421-3. doi: 10.1042/bj2150421.

DOI:10.1042/bj2150421
PMID:6651769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1152412/
Abstract

Polysaccharide material was found in the proteolysis glycopolypeptide fraction from normal human gastric mucus. The polysaccharide was identified by carbohydrate and amino acid analyses, by elemental analysis and from its behaviour on density-gradient ultracentrifugation. The polysaccharide is polydisperse with a weight-average molecular mass of 300 000 Da. Over 85% of the polysaccharide consists of galactose, and this represents 26% of all the galactose present in the fractions after beta-elimination with reduction of the glycopolypeptide material.

摘要

在正常人胃黏液的蛋白水解糖多肽组分中发现了多糖物质。通过碳水化合物和氨基酸分析、元素分析及其在密度梯度超速离心时的行为对该多糖进行了鉴定。该多糖具有多分散性,重均分子量为300000道尔顿。超过85%的多糖由半乳糖组成,这占经β-消除还原糖多肽物质后各组分中所有半乳糖的26%。

相似文献

1
The presence of polysaccharide in normal human gastric mucus.正常人体胃黏液中多糖的存在。
Biochem J. 1983 Nov 1;215(2):421-3. doi: 10.1042/bj2150421.
2
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Histochemical study of the mucosubstances in the canine stomach. I. The resting mucosa.犬胃黏膜物质的组织化学研究。I. 静息黏膜。
Am J Dig Dis. 1967 Sep;12(9):891-912. doi: 10.1007/BF02236447.
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[Electrolytes and sialic acids of gastric juice and mucus in peptic ulcer patients].[消化性溃疡患者胃液和黏液中的电解质与唾液酸]
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本文引用的文献

1
Study of the carbohydrate content of mucus glycoproteins from normal and diseased colons.正常和病变结肠黏液糖蛋白碳水化合物含量的研究。
Clin Sci (Lond). 1981 Aug;61(2):229-34. doi: 10.1042/cs0610229.
2
Gastric mucus: isolation and polymeric structure of the undegraded glycoprotein: its breakdown by pepsin.胃黏液:未降解糖蛋白的分离及其聚合结构:胃蛋白酶对其的分解
Gastroenterology. 1980 Apr;78(4):709-15.
3
Structures and immunochemical properties of oligosaccharides isolated from pig submaxillary mucins.从猪下颌粘蛋白中分离出的寡糖的结构和免疫化学性质。
J Biol Chem. 1968 Feb 10;243(3):616-26.
4
The macromolecular properties of blood-group-specific glycoproteins. Characterization of a series of fractions obtained by solvent fractionation.血型特异性糖蛋白的大分子特性。通过溶剂分级分离获得的一系列组分的表征。
Biochem J. 1974 Oct;143(1):159-70. doi: 10.1042/bj1430159.
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A gas-liquid chromatographic approach to the analysis of carbohydrates.一种用于分析碳水化合物的气-液色谱方法。
Biochem Soc Trans. 1977;5(6):1693-5. doi: 10.1042/bst0051693.
6
The biochemical and histochemical nomenclature of mucus.黏液的生化和组织化学命名法。
Br Med Bull. 1978 Jan;34(1):5-8. doi: 10.1093/oxfordjournals.bmb.a071458.
7
Mucus of the mammalian genital tract.哺乳动物生殖道的黏液。
Br Med Bull. 1978 Jan;34(1):34-8.