Hoffman J A, Chance R E
Biochem Biophys Res Commun. 1983 Nov 15;116(3):830-5. doi: 10.1016/s0006-291x(83)80217-4.
Bovine pancreatic polypeptide, a 36-residue polypeptide hormone, was successfully crystallized for the first time. During purification by extensive dialysis against distilled water a surprisingly insoluble form of the peptide was obtained which led to its crystallization as orthorhombic needles up to 2 mm in length.
牛胰多肽,一种由36个氨基酸残基组成的多肽激素,首次成功结晶。在通过对蒸馏水进行广泛透析纯化的过程中,获得了一种令人惊讶的不溶性肽形式,这使其结晶为长达2毫米的正交晶系针状晶体。