Krieger J, Kurtz D
Bull Eur Physiopathol Respir. 1983 Nov-Dec;19(6):641-4.
Pneumotachographic recording of ventilation requires an air-tight nasobuccal face-mask which might disturb the subjects' sleep and modify their breathing patterns. In a cross-over randomized study, we compared recordings obtained with and without a face-mask in 20 healthy normal volunteers (10 males, 10 females, mean age: 21.7 +/- SEM 0.5 years). The sleep modifications that resulted from the presence of the face-mask were a lengthening of the REM-sleep latency (+ 38%, p less than 0.01), an increase in intrasleep waking-time (+ 55%, p less than 0.05), an increase in sleep stage-1 duration (+ 40%, p less than 0.02), and a decrease in REM-sleep duration (-20%, p less than 0.01), resulting in a decrease in total sleep duration (-9%, p less than 0.05). The sleep-latency, the number of awakenings, the sleep stage-2 duration, the deep slow wave sleep duration, the sleep stability and the number of sleep cycles were not significantly modified. The respiratory frequency was unchanged in any of the sleep stages. No obstructive or mixed apnoea was observed during the nights when the subjects wore the face-mask. The apnoea index for central apnoeas was low and remained unchanged with and without the face-mask (0.30 +/- 0.10 and 0.35 +/- 0.10 respectively). Thus the observed modifications do not rule out the basic advantage of the pneumotachographic method, that of being the only method to-date providing a direct quantitative measurement of respiratory flow and flow rate during sleep.
通过呼吸速度描记法记录通气情况需要一个密封的口鼻面罩，这可能会干扰受试者的睡眠并改变他们的呼吸模式。在一项交叉随机研究中，我们比较了20名健康正常志愿者（10名男性，10名女性，平均年龄：21.7±标准误0.5岁）佩戴和不佩戴面罩时的记录情况。面罩的存在导致的睡眠改变包括快速眼动睡眠潜伏期延长（+38%，p<0.01）、睡眠中觉醒时间增加（+55%，p<0.05）、睡眠1期时长增加（+40%，p<0.02）以及快速眼动睡眠时长减少（-20%，p<0.01），从而导致总睡眠时间减少（-9%，p<0.05）。睡眠潜伏期、觉醒次数、睡眠2期时长、深度慢波睡眠时长、睡眠稳定性和睡眠周期数均未发生显著改变。在任何睡眠阶段，呼吸频率均未改变。受试者佩戴面罩的夜晚未观察到阻塞性或混合性呼吸暂停。中枢性呼吸暂停的呼吸暂停指数较低，佩戴和不佩戴面罩时均保持不变（分别为0.30±0.10和0.35±0.10）。因此，观察到的这些改变并不排除呼吸速度描记法的基本优势，即它是迄今为止唯一一种能够直接定量测量睡眠期间呼吸流量和流速的方法。
