在大鼠肾脏清除率研究中，氨氯地平具有保镁作用的证据。
Evidence for a magnesium-sparing action by amiloride during renal clearance studies in rats.
作者信息
Devane J, Ryan M P
出版信息
Br J Pharmacol. 1983 Aug;79(4):891-6. doi: 10.1111/j.1476-5381.1983.tb10533.x.
Abstract
The potassium-sparing diuretic, amiloride, reduced the fractional excretion of magnesium in anaesthetized rats. Alterations in glomerular filtration rate (GFR), the filtered load of magnesium, arterial blood pressure, the status of the extracellular fluid volume, plasma aldosterone concentration and acid-base balance were not involved. It was concluded that amiloride exerted a magnesium-sparing effect by a direct renal action.
摘要
保钾利尿剂阿米洛利可降低麻醉大鼠的镁排泄分数。肾小球滤过率（GFR）、镁滤过量、动脉血压、细胞外液量状态、血浆醛固酮浓度及酸碱平衡均未发生改变。得出的结论是，阿米洛利通过直接的肾脏作用发挥保镁效应。
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本文引用的文献
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Effect of aldosterone on the metabolism of magnesium.醛固酮对镁代谢的影响。
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The effects of amiloride and triamterene on urinary magnesium excretion in conscious saline-loaded rats.阿米洛利和氨苯蝶啶对清醒生理盐水负荷大鼠尿镁排泄的影响。
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The renal handling of magnesium.肾脏对镁的处理。
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Effects of chlorothiazide and amipramizide (MK 870) on the renal excretion of calcium, phosphate and magnesium.氯噻嗪和阿米普明（MK 870）对钙、磷和镁肾排泄的影响。
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[Studies of the effect of the diuretics furosemide, ethacrynic acid and triamterene on renal magnesium and calcium excretion].[利尿剂速尿、依他尼酸和氨苯蝶啶对肾脏镁和钙排泄影响的研究]
Klin Wochenschr. 1967 Mar 15;45(6):313-4. doi: 10.1007/BF01747104.
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