Debski L, Dzierzkowska J, Kaleta Z, Maśliński S
Acta Physiol Pol. 1978 Jan-Feb;29(1):61-6.
Effect of low body temperature on gastric secretory activity in the guinea pig under urethane general anaesthesia. Acta Physiol. Pol., 1978, 29 (1): 61-66. The effect of low body temperature on spontaneous and histamine (H) stimulated or Nalpha Nalpha-dimethylhistamine (NDMH)-stimulated gastric secretion was investigated in the guinea pig under general anaesthesia with urethane. In normothermia NDMH had a stronger stimulatory action on acid secretion In hypothermia (30 degrees C and 25 degrees C) only NDMH showed some stimulating effect. The obtained results point to the necessity of strict controlling of body temperature in the experiments performed on animals under general anaesthesia and suggest that the lack of effect at low temperature may be connected with an inhibition of the processes of H side-chain methylation when the rate of metabolic processes in the organism has fallen.
体温降低对氨基甲酸乙酯全身麻醉下豚鼠胃分泌活动的影响。《波兰生理学杂志》，1978年，第29卷第1期：61 - 66页。研究了在氨基甲酸乙酯全身麻醉下，体温降低对豚鼠自发的以及组胺（H）刺激或Nα - Nα - 二甲基组胺（NDMH）刺激的胃分泌的影响。在正常体温下，NDMH对胃酸分泌有更强的刺激作用。在低温（30摄氏度和25摄氏度）时，只有NDMH显示出一定的刺激作用。所得结果表明，在对全身麻醉的动物进行实验时，严格控制体温是必要的，并且提示低温时缺乏效应可能与机体代谢过程速率下降时H侧链甲基化过程受到抑制有关。
