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一项关于Imugard IG500白细胞去除过滤器常规使用的研究,阐明了输血反应的一种可能原因及一种预防方法。

A study of the routine use of the Imugard IG500 Leukocyte Removal Filter illustrating a possible cause of transfusion reactions and a method of prevention.

作者信息

McGregor M, Harrison J F, Kirkham R

出版信息

Clin Lab Haematol. 1983;5(3):279-85. doi: 10.1111/j.1365-2257.1983.tb01365.x.

DOI:10.1111/j.1365-2257.1983.tb01365.x
PMID:6653062
Abstract

The results of the use of the Imugard IG500 Leukocyte Removal Filter in the transfusion of 100 patients requiring leucocyte poor blood are presented. The patients were suffering from a variety of disorders. Many of them had previously received leucocyte poor blood prepared by other methods. Five patients developed non-haemolytic transfusion reactions. Subsequent investigations suggested that these were reactions to the plasma proteins present in the leucocyte poor blood prepared by filtration. A simple method of removal of these plasma proteins combined with filtration is described. The resultant product has been transfused, without incident, into the patients who previously reacted.

摘要

本文介绍了使用Imugard IG500白细胞去除过滤器为100名需要少白细胞血液的患者进行输血的结果。这些患者患有多种疾病。他们中的许多人此前曾接受过通过其他方法制备的少白细胞血液。有5名患者发生了非溶血性输血反应。后续调查表明,这些反应是对通过过滤制备的少白细胞血液中存在的血浆蛋白产生的反应。本文描述了一种结合过滤去除这些血浆蛋白的简单方法。由此得到的产品已被输注给先前有反应的患者,且未发生任何不良反应。

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