Vaknine R, Schlegel W, Lorenz W J, Bruehl P
Eur J Nucl Med. 1983;8(10):416-20. doi: 10.1007/BF00252938.
The curvature scintigram is an image, obtained by applying the Laplace operator to nuclear medicine images, that shows local variations of count rate density. Applications to liver scintigrams are described. The diagnostic quality of the curvature scintigram is compared with that of the conventional and digitally filtered scintigrams, using a series of patients who have been categorized by histology or by transmission computer tomography. From our results, the curvature scintigram demonstrates an improvement over the subjective findings of clinicians. It enables the detection of an increased number of true-positives and a reduced number of false-positives.
曲率闪烁图是通过将拉普拉斯算子应用于核医学图像而获得的一种图像，它显示了计数率密度的局部变化。文中描述了其在肝脏闪烁图中的应用。使用一系列经组织学或透射计算机断层扫描分类的患者，将曲率闪烁图的诊断质量与传统闪烁图和数字滤波闪烁图的诊断质量进行了比较。根据我们的结果，曲率闪烁图显示出优于临床医生主观判断的效果。它能够检测出更多的真阳性病例，并减少假阳性病例的数量。
