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论DNA中长重复序列与核内不均一RNA的互补性。

On the complementarity of long repeated sequences in DNA to hnRNA.

作者信息

Lin H J

出版信息

Experientia. 1983 Dec 15;39(12):1390-2. doi: 10.1007/BF01990120.

Abstract

Long repeated sequences containing up to 18,000 base pairs were found in a human DNA fraction isolated with the nuclease S1-dioxane method. Hybridization studies showed that the long repeats contained a greater proportion of sequences complementary to hnRNA than short repeats. They also exhibited homology to the latter, as shown by cross-hybridization experiments.

摘要

在用核酸酶S1 - 二氧六环法分离出的人类DNA组分中发现了含有多达18000个碱基对的长重复序列。杂交研究表明,与短重复序列相比,长重复序列中与核内不均一RNA(hnRNA)互补的序列比例更高。如交叉杂交实验所示,它们与短重复序列也表现出同源性。

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