Kilpatrick L, Gavine F, Apps D, Phillips J
FEBS Lett. 1983 Dec 12;164(2):383-8. doi: 10.1016/0014-5793(83)80322-6.
The matrix of the chromaffin granule contains a family of acidic proteins, collectively known as the chromogranins. It has been suggested that this family results from protease action on the major component, chromogranin A. Evidence for this has now been obtained from in vitro translation of adrenal medullary messenger RNA and immunoprecipitation of translation products using an antiserum directed against chromogranin A, but which also recognises other chromogranins.
嗜铬粒蛋白的基质包含一族酸性蛋白，统称为嗜铬粒蛋白。有人提出，这一族蛋白是蛋白酶作用于主要成分嗜铬粒蛋白A的结果。现在，通过肾上腺髓质信使核糖核酸的体外翻译以及使用针对嗜铬粒蛋白A但也能识别其他嗜铬粒蛋白的抗血清对翻译产物进行免疫沉淀，已获得了这方面的证据。
