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非麻痹性运动障碍和言语障碍：辅助运动区的作用。

Non-paralytic motor disturbances and speech disorders: the role of the supplementary motor area.

作者信息

Gelmers H J

出版信息

J Neurol Neurosurg Psychiatry. 1983 Nov;46(11):1052-4. doi: 10.1136/jnnp.46.11.1052.

DOI:10.1136/jnnp.46.11.1052
PMID:6655481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC491745/
Abstract

A right-handed patient with a lesion demonstrated by CT to involve the right medial frontal cortex is described. He exhibited a strong contralateral grasp reflex, motor perseveration and the presence of purposeful movements that appeared to be dissociated from conscious volition. In addition, there was a disorder of speech consisting of a lack of spontaneous speech production, with preserved ability to imitate. It is suggested that these disorders are due to damage to the supplementary motor area.

摘要

描述了一名右利手患者，CT显示其右侧额叶内侧皮质有病变。他表现出强烈的对侧抓握反射、运动持续性，以及一些看似与有意识意志分离的有目的运动。此外，还存在一种言语障碍，表现为缺乏自发言语表达能力，但模仿能力保留。提示这些障碍是由于辅助运动区受损所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef3e/491745/460671ef0769/jnnpsyc00043-0091-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef3e/491745/460671ef0769/jnnpsyc00043-0091-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef3e/491745/460671ef0769/jnnpsyc00043-0091-a.jpg

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本文引用的文献

1
The aphasia syndrome of stroke in the left anterior cerebral artery territory.
Arch Neurol. 1980 Feb;37(2):97-100. doi: 10.1001/archneur.1980.00500510055010.
2
Supplementary motor area and other cortical areas in organization of voluntary movements in man.辅助运动区及其他皮质区在人类自主运动组织中的作用
J Neurophysiol. 1980 Jan;43(1):118-36. doi: 10.1152/jn.1980.43.1.118.
3
Cortical organization of voluntary motor activity as revealed by measurement of regional cerebral blood flow.通过测量局部脑血流量揭示的随意运动活动的皮质组织。
辅助运动区综合征对平衡运动发起与抑制的启示。
Front Hum Neurosci. 2014 Nov 28;8:960. doi: 10.3389/fnhum.2014.00960. eCollection 2014.
4
Paroxysmal alien hand syndrome.阵发性异己手综合征
J Neurol Neurosurg Psychiatry. 1993 Jul;56(7):788-92. doi: 10.1136/jnnp.56.7.788.
5
Primitive reflexes in healthy, adult volunteers and neurological patients: methodological issues.健康成年志愿者和神经疾病患者的原始反射：方法学问题
J Neurol. 1993 Sep;240(8):495-504. doi: 10.1007/BF00874119.
J Neurol Sci. 1981 Nov-Dec;52(2-3):149-61. doi: 10.1016/0022-510x(81)90001-0.
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Medial frontal cortex infarction and the alien hand sign.
Arch Neurol. 1981 Nov;38(11):683-6. doi: 10.1001/archneur.1981.00510110043004.
5
The aprosodias. Functional-anatomic organization of the affective components of language in the right hemisphere.失韵律症。右半球语言情感成分的功能-解剖组织
Arch Neurol. 1981 Sep;38(9):561-9. doi: 10.1001/archneur.1981.00510090055006.
6
The grasp reflex and perseveration.握持反射和持续性动作。
Brain. 1970;93(1):181-92. doi: 10.1093/brain/93.1.181.
7
Variations in regional cortical blood flow in the right and left hemispheres during automatic speech.自动言语过程中左右半球局部皮质血流的变化。
Brain. 1978 Jun;101(2):193-209. doi: 10.1093/brain/101.2.193.
8
Aphasia following infarction of the left supplementary motor area: a clinicopathologic study.左侧辅助运动区梗死所致失语：一项临床病理研究。
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9
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Science. 1979 Nov 16;206(4420):847-50. doi: 10.1126/science.493986.