Gelmers H J
J Neurol Sci. 1981 Nov-Dec;52(2-3):149-61. doi: 10.1016/0022-510x(81)90001-0.
Regional cerebral blood flow (rCBF) was measured in conjunction with carotid angiography using the intra-arterial xenon-133 injection method. Measurements were made in 9 patients in the left hemisphere and in 6 patients in the right hemisphere. It was confirmed that there was no significant differences in the blood flow, in either the right or the left hemisphere, between measurements taken while patients carried out various types of voluntary activity and preceding measurements of total mean hemisphere blood flow taken during rest. However, the pattern of flow distribution changed significantly during various types of voluntary motor activity, In general, the contralateral Rolandic motor and sensory areas were activated during execution of voluntary movements. The supplementary motor area appears to play a major role in the integration of information from various cortical regions; such integration is, of course, necessary in the preparation of the ultimate motor action.
采用动脉内注入氙 - 133 法，结合颈动脉血管造影术测量局部脑血流量（rCBF）。对 9 例患者的左半球和 6 例患者的右半球进行了测量。结果证实，在患者进行各种类型的自主活动时所测得的血流量，与之前在休息期间测得的全脑半球平均血流量相比，无论是右半球还是左半球，均无显著差异。然而，在各种类型的自主运动活动期间，血流分布模式发生了显著变化。一般来说，在执行自主运动时，对侧的中央前回运动和感觉区域会被激活。辅助运动区似乎在整合来自各个皮质区域的信息方面发挥着主要作用；当然，这种整合在准备最终的运动动作时是必要的。
