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儿童急性风湿热相关的皮纹改变

Dermatoglyphic alterations associated with acute rheumatic fever in children.

作者信息

Sanyal S K, Mukerjee D P, Ahmed S H

出版信息

Am J Dis Child. 1978 Jul;132(7):692-5. doi: 10.1001/archpedi.1978.02120320052012.

DOI:10.1001/archpedi.1978.02120320052012
PMID:665597
Abstract

The dermatoglyphic configurations of 78 children with acute rheumatic fever were compared with those of 46 first-degree relatives and 1,310 normal subjects. Of the children with acute rheumatic fever, 75% had an ulnar deviation of the axial triradius. In about 40% of this group, the ulnar deviation was associated with a concomitant distal displacement, which resulted in a significantly higher mean maximal angle atd (P less than .001) and significantly lower mean ab and td ridge counts (P less than .001) relative to normal control values. The palmar dermatoglyphics of patients with acute rheumatic fever were more closely related to the configurations of first-degree relatives than to normal controls. The dermatoglyphic profiles of six patients were nearly identical to those of their first-degree relatives, all of whom had a history of acute rheumatic fever. Presence of abnormal dermatoglyphic profiles in a large proportion of children with acute rheumatic fever supports the hypothesis that certain individuals have a genetic predisposition to this disease.

摘要

将78例急性风湿热患儿的皮纹形态与46例一级亲属及1310例正常受试者的皮纹形态进行了比较。在急性风湿热患儿中,75%的人轴三角向尺侧偏移。在该组中约40%的人,尺侧偏移伴有远端移位,相对于正常对照值,这导致平均最大atd角显著更高(P<0.001),平均ab和td嵴纹计数显著更低(P<0.001)。急性风湿热患者的手掌皮纹与一级亲属的形态比与正常对照的关系更密切。6例患者的皮纹图谱与其一级亲属几乎相同,所有一级亲属均有急性风湿热病史。大部分急性风湿热患儿存在异常皮纹图谱,这支持了某些个体对该病有遗传易感性这一假说。

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