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精神分裂症的遗传负荷:一项皮纹学研究。

Genetic loadings in schizophrenia: a dermatoglyphic study.

作者信息

Balgir R S, Murthy R S, Wig N N

机构信息

Department of Hematology, Regional Medical Research Center, Bhubaneswar, Orissa, India.

出版信息

Isr J Med Sci. 1993 May;29(5):265-8.

PMID:8314683
Abstract

Finger and palmar dermatoglyphics of 120 male and 120 female schizophrenics with and without a family history of schizophrenia in first-degree relatives were studied in the northwestern part of India. Patients were selected according to specific diagnostic criteria. Significant dermatoglyphic differences were observed for fingerprint patterns, total finger ridge counts and 'atd' angle between the schizophrenics with and those without a positive family history of schizophrenia, suggesting a strong "genetic loading" (i.e., hereditary factors) in familial cases of schizophrenia. Dermatoglyphic features of isolated schizophrenics also significantly differed from those of controls, thus indicating the involvement of genetic factors in the etiology of schizophrenia.

摘要

在印度西北部,对120名男性和120名女性精神分裂症患者的指纹和掌纹皮纹进行了研究,这些患者有无一级亲属精神分裂症家族史。患者根据特定诊断标准选取。在有精神分裂症家族史阳性和无精神分裂症家族史阳性的精神分裂症患者之间,观察到指纹模式、总指嵴数和“atd角”存在显著的皮纹差异,这表明在精神分裂症家族病例中存在强烈的“遗传负荷”(即遗传因素)。散发性精神分裂症患者的皮纹特征也与对照组有显著差异,从而表明遗传因素参与了精神分裂症的病因学。

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引用本文的文献

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Pedigree analysis and dermatoglyphic features of probands with schizophrenia and their affected gender-matched parents: A cross-sectional comparative study.精神分裂症先证者及其性别匹配的患病父母的系谱分析和皮纹特征:一项横断面比较研究。
Indian J Psychiatry. 2025 Aug;67(8):798-803. doi: 10.4103/indianjpsychiatry_558_24. Epub 2025 Aug 15.
2
Parent-of-origin Effect in Schizophrenia and Non-affective Psychoses: Evidence from Dermatoglyphics.精神分裂症和非情感性精神病的亲源效应:来自皮纹学的证据。
Indian J Psychol Med. 2013 Jul;35(3):260-7. doi: 10.4103/0253-7176.119481.
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Dermatoglyphics in patients with schizophrenia.
精神分裂症患者的皮纹学
J Res Med Sci. 2011 Aug;16(8):1055-61.