Giani M, Picca M, Saccaggi A, Capitanio L, Galato R, Bettinelli A, Teotino N, Ghio L, Edefonti A
Proc Eur Dial Transplant Assoc. 1983;20:201-6.
To improve nitrogen balance and nutritional status, 10 paediatric patients (11.2 +/- 2.7 years; 28.5 +/- 5.1 kg) on regular haemodialysis (HD) for 25.3 +/- 1.2 months were treated with haemofiltration (HF) for 12.2 +/- 3.4 months. HF was prescribed using a urea kinetic model to ensure a pre-treatment blood urea nitrogen (BUN) of 130 mg/100ml. Urea generation rate (Gu) and protein catabolic rate (PCR) were computed by urea kinetics. Protein and calorie intake was assessed in the children on an unrestricted diet by analysis of 10 days' dietary records obtained every two months. During HF treatment a significant decrease of Gu and PCR was obtained and nitrogen balance increased in all the children.
为改善氮平衡和营养状况，对10例接受常规血液透析（HD）25.3±1.2个月的儿科患者（年龄11.2±2.7岁；体重28.5±5.1kg）进行了12.2±3.4个月的血液滤过（HF）治疗。使用尿素动力学模型开具血液滤过处方，以确保治疗前血尿素氮（BUN）为130mg/100ml。通过尿素动力学计算尿素生成率（Gu）和蛋白质分解代谢率（PCR）。通过分析每两个月获取的10天饮食记录，对饮食不受限制的儿童的蛋白质和热量摄入进行评估。在血液滤过治疗期间，所有儿童的Gu和PCR均显著降低，氮平衡增加。
