Desmons F, Bergoend H, Rotteleur G
Phlebologie. 1983 Oct-Dec;36(4):329-36.
The authors report two original cases of profuse pigmentation associated with proliferative lesions of the lower limbs, in patients with venous incompetence, suggestive if the syndrome described by Mali and al. in 1963. One case was in fact of Kaposi's disease associated with severe thrombocytopenia which was the cause of death, despite the use of Chloraminophene-Cortancyl. The other case was a woman with profuse pigmentation of the lower limbs associated with multiple disseminated lesions of allergic vasculitis, probably of drug origin. Suppression of the drug and rest led to a marked improvement in the lesions. Although very different from each other, both of these cases are suggestive of Mali's syndrome, but their treatment was totally opposite. The first case, a real vascular neoplasia, required the combination of antimitotic-steroid ; the second case, on the contrary, resolved with rest and a simple elastic bandage, like allcutaneous venous lesions, in particular Mali's syndrome.
作者报告了两例与下肢增殖性病变相关的大量色素沉着的原始病例，患者存在静脉功能不全，提示为1963年Mali等人描述的综合征。其中一例实际上是伴有严重血小板减少症的卡波西氏病，尽管使用了氯胺苯砜 - 考坦西尔，但这仍是导致死亡的原因。另一例是一名女性，下肢有大量色素沉着，伴有过敏性血管炎的多处播散性病变，可能源于药物。停用药物并休息后，病变明显改善。尽管这两例病例彼此差异很大，但均提示为马里氏综合征，但其治疗方法却完全相反。第一例是真正的血管肿瘤，需要抗有丝分裂药物与类固醇联合使用；相反，第二例像所有皮肤静脉病变，特别是马里氏综合征一样，通过休息和简单的弹性绷带包扎而痊愈。
