鸡颈二腹肌在黑寡妇蜘蛛毒液中α- 拉毒素生物测定中的应用。
Use of chick biventer cervicis muscle in the bioassay of alpha-latrotoxin from black widow spider venom.
作者信息
Tzeng M C, Tian S S
出版信息
Toxicon. 1983;21(6):879-81. doi: 10.1016/0041-0101(83)90077-6.
PMID:6658809
Abstract
alpha-Latrotoxin purified from black widow spider venom caused a sustained contraction of the chick biventer cervicis muscle. Muscle response to exogenous acetylcholine was not impaired. The time to reach half maximal contracture height was reproducible with small variations and can be used to quantitate the activity of alpha-LTX preparations.
摘要
从黑寡妇蜘蛛毒液中纯化得到的α-拉毒素可使鸡双腹直肌产生持续收缩。肌肉对外源性乙酰胆碱的反应并未受损。达到最大挛缩高度一半所需的时间具有可重复性，变化较小，可用于定量α-LTX制剂的活性。
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