Ziskoven R, Achenbach C, Schulten H R, Roll R
Toxicol Lett. 1983 Dec;19(3):225-31. doi: 10.1016/0378-4274(83)90123-6.
The transfer of T1+ cations through the placental barrier of pregnant mice and rats was studied by comparing the thallium concentrations in the maternal brain and kidney and those in fetal tissue at times of 10 min to 50 h after dosage of the animals with 10 mg/kg body wt. T1(2)SO4. The quantitative determinations were performed with field desorption mass spectrometry after dilution of the homogenised tissue samples with enriched stable isotopes of thallium. The total sample quantity required for one complete assay is 1-3 micrograms, the analysis time for one determination about 30 min.
通过比较给予体重为10mg/kg的T1(2)SO4的怀孕小鼠和大鼠在给药后10分钟至50小时时母体大脑和肾脏以及胎儿组织中的铊浓度，研究了T1+阳离子通过胎盘屏障的情况。在用富含铊的稳定同位素稀释匀浆组织样品后，用场解吸质谱法进行定量测定。一次完整测定所需的总样品量为1-3微克，一次测定的分析时间约为30分钟。
