Nachev S, Zlateva M, Mishev B
Vutr Boles. 1983;22(2):120-3.
The authors present one lethal case of primary pulmonary hypertension (PPH) in a male of 40. The pathomorphological examination revealed very characteristic changes in the vessels of the lungs. Often slot-like canals were found, with proliferated myoepithelial cells, connecting the lumena of vessels with thickened walls with thin-wall vessels ("plexiform changes") or with vessels with sinusoidal-cavernous type ("angiomatoid formations"). Those vascular changes are in a strong contrast with the absence of inflammatory alterations in the lungs. The possibilities of developing of similar vascular changes in the lungs, leading to PPH are discussed in accordance with the up-to date literature data.
作者报告了一例40岁男性原发性肺动脉高压（PPH）致死病例。病理形态学检查显示肺部血管有非常典型的变化。常发现呈裂隙状的管道，伴有增生的肌上皮细胞，将壁厚的血管腔与薄壁血管（“丛状改变”）或与窦状-海绵状型血管（“血管瘤样结构”）相连。这些血管变化与肺部无炎症改变形成强烈对比。根据最新文献数据，讨论了肺部发生类似血管变化导致PPH的可能性。
