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局部应用泼尼松龙降低兔房水中透明质酸盐浓度

Reduction of the hyaluronate concentration in rabbit aqueous humour by topical prednisolone.

作者信息

Laurent U B

出版信息

Acta Ophthalmol (Copenh). 1983 Oct;61(5):751-5. doi: 10.1111/j.1755-3768.1983.tb01456.x.

DOI:10.1111/j.1755-3768.1983.tb01456.x
PMID:6659883
Abstract

Rabbits were treated topically with prednisolone for 5 or 10 days and aqueous humour removed immediately after treatment as well as 10 and 20 days later. The hyaluronate concentration was significantly lower in the treated eyes compared to control eyes. It returned to the normal level after withdrawal of the drug. Repeated sampling of aqueous humour at intervals of 10 days did not influence the hyaluronate concentration in the control group.

摘要

给兔子局部使用泼尼松龙治疗5天或10天,治疗后以及10天和20天后立即采集房水。与对照眼相比,治疗眼的透明质酸盐浓度显著降低。停药后其恢复到正常水平。对照组每隔10天重复采集房水对透明质酸盐浓度没有影响。

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