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[实验性上腔静脉结扎时大脑皮质的血管变化]

[Vascular changes in the cerebral cortex in experimental ligation of the superior vena cava].

作者信息

Nasyrova I I

出版信息

Arkh Anat Gistol Embriol. 1983 Nov;85(11):72-9.

PMID:6661060
Abstract

Venous congestion in the cerebral hemispheres produced by means of the anterior vena cava ligation is accompanied with an uneven character of vascular changes in the hemisphere cortex. Under the same experimental conditions, manifestations of the venous congestion in different animals can have a light, middle and severe degree, each of them being characterized with its own morphological and quantitative peculiarities. The disturbance of the venous outflow from the hemisphere cortex results in certain changes not only in the venous and capillary, but also in the arterial part of the blood bed. The manifestation of the vascular changes can be different: from a comparatively light venous plethora up to multiple venous and arterial hemorrhages. The ligation of the anterior vena cava in all cases produces an acute venous congestion in the cerebral hemisphere cortex, its manifestations begin gradually to compensate and normalize after the first two days. The process is gradually completing by the end of the first month, although consequences of the vascular changes remain in the cortex during a long period of time. A variant of the venous congestion course is revealed when during 1.5-2.5 months a decompensation stage as a manifestation of some secondary disorder in the venous stream in the anterior vena cava system is developing. Certain unevenness in distribution of the vascular changes throughout the hemisphere areas is revealed; it is connected with peculiarities of the anatomical structure of different parts of the cortical blood bed.

摘要

通过结扎前腔静脉造成的大脑半球静脉充血,伴随着半球皮质血管变化的不均衡特征。在相同的实验条件下,不同动物的静脉充血表现可分为轻度、中度和重度,每种程度都有其自身的形态学和定量特点。半球皮质静脉流出受阻不仅会导致静脉和毛细血管发生某些变化,还会使血床的动脉部分发生变化。血管变化的表现可能各不相同:从相对较轻的静脉充血到多发性静脉和动脉出血。在所有情况下,结扎前腔静脉都会在大脑半球皮质产生急性静脉充血,其表现在前两天后开始逐渐代偿并恢复正常。尽管血管变化的后果会在很长一段时间内留在皮质中,但该过程在第一个月末逐渐完成。当在1.5 - 2.5个月期间出现失代偿阶段,作为前腔静脉系统静脉血流中某些继发性紊乱的表现时,会发现静脉充血过程的一种变体。整个半球区域的血管变化分布存在一定的不均衡性;这与皮质血床不同部位的解剖结构特点有关。

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