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背侧束损伤对序列条件反射和痕迹条件反射的影响。

The effects of dorsal bundle lesions on serial and trace conditioning.

作者信息

Tsaltas E, Preston G C, Gray J A

出版信息

Behav Brain Res. 1983 Dec;10(2-3):361-74. doi: 10.1016/0166-4328(83)90040-2.

DOI:10.1016/0166-4328(83)90040-2
PMID:6661283
Abstract

The performance of rats with neurotoxic lesions of the dorsal ascending noradrenergic bundle (DB) was compared with that of sham-operated control animals under two behavioural conditions. Animals with DB lesions were slower than controls to acquire a classically-conditioned emotional response (conditioned suppression) with a trace interval interposed between the clicker conditioned stimulus (CS) and the shock reinforcer. However, if the latter half of the trace interval was filled by a second stimulus, a light, the DB-lesioned animals acquired conditioned suppression to the clicker faster than did controls under the same conditions. These results are discussed in terms of the attentional theory of DB function.

摘要

在两种行为条件下,对具有背侧上行去甲肾上腺素能束(DB)神经毒性损伤的大鼠与假手术对照动物的表现进行了比较。与对照动物相比,患有DB损伤的动物在习得经典条件性情绪反应(条件性抑制)时速度较慢,在点击条件刺激(CS)和电击强化刺激之间插入了一个痕迹间隔。然而,如果痕迹间隔的后半部分由第二个刺激(一个光)填充,那么在相同条件下,患有DB损伤的动物比对照动物更快地对点击器产生条件性抑制。根据DB功能的注意理论对这些结果进行了讨论。

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