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红核损伤会破坏兔子经典条件反射性瞬膜反应。

Red nucleus lesions disrupt the classically conditioned nictitating membrane response in rabbits.

作者信息

Rosenfield M E, Moore J W

出版信息

Behav Brain Res. 1983 Dec;10(2-3):393-8. doi: 10.1016/0166-4328(83)90043-8.

DOI:10.1016/0166-4328(83)90043-8
PMID:6661285
Abstract

Sixteen rabbits received classical conditioning of the right nictitating membrane response using a tone CS and electrostimulation of the right eye as the US. Single electrocoagulating RF lesions of the medial portion of the left magnocellular red nucleus eliminated or severely reduced the previously acquired conditioned response. This finding is consistent with the idea that an essential anatomical substrate of the conditioned response includes a circuit from the cerebellum to the contralateral red nucleus which projects contralaterally in turn to pontine motoneurons mediating the defensive nictitating membrane response.

摘要

16只兔子接受了经典条件反射实验,以音调作为条件刺激(CS),右眼电刺激作为非条件刺激(US),来训练右侧瞬膜反应。对左侧大细胞红核内侧部分进行单次射频电凝损伤,消除或严重降低了先前习得的条件反应。这一发现与以下观点一致,即条件反应的一个重要解剖学基础包括一个从小脑到对侧红核的回路,该回路继而对侧投射到介导防御性瞬膜反应的脑桥运动神经元。

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Red nucleus lesions disrupt the classically conditioned nictitating membrane response in rabbits.红核损伤会破坏兔子经典条件反射性瞬膜反应。
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