Caratero C, Malecaze F, Caratero A, Planel H, Bec P
Bull Assoc Anat (Nancy). 1983 Jun;67(197):169-80.
The ultra-structural study of the photoreceptors in the human retina during the aging process was carried out by comparing two groups of patient: 6 young subjects under 25 years of age, and 6 older subjects over 70. Retinal samples were taken from the posterior pole and treated with the classical techniques of electron microscopy. Our works show that during the aging process, nuclear and cytoplasmic morphological modifications are observed. The observation about nuclear modifications is in full agreement with aging process theories according to which the genome plays an essential part. On the other hand, no modification of the external article could be so far observed. Further works will perhaps allow to discover a decrease of the renewal process of the photoreceptor discs.
6名25岁以下的年轻受试者和6名70岁以上的老年受试者。从后极取出视网膜样本，并用经典的电子显微镜技术进行处理。我们的研究表明，在衰老过程中，观察到细胞核和细胞质的形态学改变。关于细胞核改变的观察结果与衰老过程理论完全一致，根据该理论基因组起着至关重要的作用。另一方面，到目前为止尚未观察到外部节段的改变。进一步的研究可能会发现光感受器盘更新过程的减少。
