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对水中石棉、消化系统癌症和人口密度之间相互关系的图形分析。

A graphical analysis of the interrelationships among waterborne asbestos, digestive system cancer and population density.

作者信息

Tarter M E, Cooper R C, Freeman W R

出版信息

Environ Health Perspect. 1983 Nov;53:79-89. doi: 10.1289/ehp.835379.

DOI:10.1289/ehp.835379
PMID:6662097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1569086/
Abstract

Five statistical procedures were used to partial the correlation between waterborne asbestos and digestive site cancer for the putative effects of population density. These include: analysis based on a data subset with roughly homogeneous population density; standard residual analysis (partial correlation); conditional probability integral transformation; analysis based upon ranked data, and use of logarithmic transformation. Nonparametric regression graphical techniques are applied to examine the nature or shape of the asbestos-cancer dose-response curve. Evidence is presented that suggests that there is considerable difference between analyses involving nonhigh-density tracts and non-San Francisco tracts. Evidence is also presented that the modal-type nonparametric regression curve forks or bifurcates when adjustment is made for population density.

摘要

采用了五种统计方法来分离水源性石棉与消化器官癌症之间的相关性,以排除人口密度的假定影响。这些方法包括:基于人口密度大致均匀的数据子集进行分析;标准残差分析(偏相关);条件概率积分变换;基于排序数据的分析以及对数变换的运用。应用非参数回归图形技术来检验石棉-癌症剂量反应曲线的性质或形状。有证据表明,涉及非高密度区域和非旧金山区域的分析之间存在相当大的差异。还有证据表明,在对人口密度进行调整时,模态型非参数回归曲线会分叉。

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本文引用的文献

1
Asbestos in drinking water and cancer incidence in the San Francisco Bay area.旧金山湾区饮用水中的石棉与癌症发病率
Am J Epidemiol. 1980 Jul;112(1):54-72. doi: 10.1093/oxfordjournals.aje.a112976.
2
Interactive editing of biomedical data.生物医学数据的交互式编辑。
Comput Programs Biomed. 1976 Jul;6(2):117-23. doi: 10.1016/0010-468x(76)90033-7.
3
Biocomputational methodology an adjunct to theory and applications.生物计算方法——理论与应用的辅助手段。
Biometrics. 1979 Mar;35(1):9-24.