Kelly J J, Mellinger J F, Sundt T M
Ann Neurol. 1978 Apr;3(4):338-43. doi: 10.1002/ana.410030411.
During the 13-year period 1964 through 1976, 37 patients less than 20 years with an intracranial, parenchymal arteriovenous fistula were seen at the Mayo Clinic. The most frequent mode of presentation was hemorrhage or seizure. Other than angiography, computed tomography with contrast enhancement was the most helpful diagnostic test. Surgery was restricted to patients with intraparenchymal hematomas, intractable seizures, or subarachnoid hemorrhage with accessible lesions and to 1 infant with a massive, sumptomatic malformation. Surgery generally was tolerated well, with reversal of most acute focal neurological deficits related to hematomas. In the nonsurgical group, follow-up revealed a fairly stable neurological status during the period of the study.
在1964年至1976年的13年期间，梅奥诊所共接诊了37例年龄小于20岁的颅内实质动静脉瘘患者。最常见的临床表现是出血或癫痫发作。除血管造影外，增强计算机断层扫描是最有用的诊断检查。手术仅限于患有脑实质内血肿、顽固性癫痫发作或蛛网膜下腔出血且病变易于处理的患者，以及1例患有巨大、有症状畸形的婴儿。手术耐受性一般良好，大多数与血肿相关的急性局灶性神经功能缺损得以恢复。在非手术组中，随访显示在研究期间神经状态相当稳定。
