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脑动静脉畸形。112例手术治疗与保守治疗的对比结果。

Cerebral arteriovenous malformations. Comparative results of surgical vs conservative treatment in 112 cases.

作者信息

Abad J M, Alvarez F, Manrique M, Garcia-Blazquez M

出版信息

J Neurosurg Sci. 1983 Jul-Sep;27(3):203-10.

PMID:6663354
Abstract

A group of 112 patients affected by cerebral arteriovenous malformations is reviewed. Sixty-six per cent of the cases presented with subarachnoid hemorrhage. Epilepsy was the main clinical feature in 20% of the cases. In 45 cases an intracerebral or intraventricular hematoma was diagnosed by CT-scan, angiography or was found during surgery. Seventy cases (62.5%) were operated upon and 42 cases were treated conservatively. In 57 operated cases, total excision of the AVM was confirmed by postoperative angiography. In this group there was no rebleeding during the follow-up period. Other 13 cases were submitted to partial excision of the AVM or clipping of the feeding vessels. In this latter group, 2 patients had later subarachnoidal rebleeding. Operative mortality was 11% in this series. Mortality caused by the AVM in the non-operated group was 20%. Comparing the morbidity in both groups, the operated group had a much better clinical evolution than the non-operated one. Regarding the final clinically results, an abnormal state of consciousness before surgery, a large size of the AVM and the presence of intracerebral hematoma appear to have a bad prognosis significance.

摘要

回顾了一组112例患有脑动静脉畸形的患者。66%的病例表现为蛛网膜下腔出血。癫痫是20%病例的主要临床特征。45例经CT扫描、血管造影或手术中发现脑内或脑室内血肿。70例(62.5%)接受了手术,42例接受了保守治疗。57例手术病例术后血管造影证实动静脉畸形完全切除。该组在随访期间无再出血。另外13例接受了动静脉畸形部分切除或供血血管夹闭。在后一组中,2例患者后来发生蛛网膜下腔再出血。该系列手术死亡率为11%。非手术组动静脉畸形导致的死亡率为20%。比较两组的发病率,手术组的临床进展比非手术组好得多。关于最终临床结果,术前意识状态异常、动静脉畸形体积大以及存在脑内血肿似乎具有不良预后意义。

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