Ohkawa H, Ohishi N, Yagi K
J Nutr Sci Vitaminol (Tokyo). 1983 Oct;29(5):515-22. doi: 10.3177/jnsv.29.515.
To investigate the metabolism of riboflavin, [2-14 C]-riboflavin was administered orally to a rat. The urine pooled for 24h after administration was fractionated by paper and silica gel thin layer chromatographies using various solvent systems. Among the radioactive metabolites, riboflavinyl glucoside was found along with 7-carboxy lumichrome and 8-carboxy lumichrome. The radioactivity of riboflavinyl glucoside comprised about 6% of the total radioactivity excreted in the urine during 24h.
为研究核黄素的代谢情况,给一只大鼠口服[2-¹⁴C] -核黄素。给药后收集24小时的尿液,使用各种溶剂系统通过纸层析和硅胶薄层层析对其进行分离。在放射性代谢产物中,发现了核黄素葡萄糖苷以及7-羧基光色素和8-羧基光色素。核黄素葡萄糖苷的放射性约占24小时内尿液中排泄的总放射性的6%。