Wynne J M, Williams G L, Ellman B A
Arch Dis Child. 1978 May;53(5):396-400. doi: 10.1136/adc.53.5.396.
Accidental intra-arterial injection of intramuscular antibiotic preparations is described in 3 cases in infants. In 2 benzathine penicillin was injected, and in 1 rolitetracycline. The clinical features are dominated by arteriolar obstruction which produces gangrene of the most severely affected limb. In addition, neuroloigcal involvement occurs when vessels to nerves or spinal cord are involved. The arteriolateral aspect of the thigh is preferable to the buttock as a site for intramuscular injection, and a short (2.5 cm) needle should be used to minimise the risk of intra-arterial injection.
本文描述了3例婴儿意外动脉内注射肌肉用抗生素制剂的病例。其中2例注射的是苄星青霉素，1例注射的是罗利环素。临床特征主要为小动脉阻塞，可导致受影响最严重的肢体发生坏疽。此外，当供应神经或脊髓的血管受累时，会出现神经方面的病变。作为肌肉注射部位，大腿外侧比臀部更可取，且应使用短（2.5厘米）针头以尽量降低动脉内注射的风险。
