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特布他林在急性产时胎儿酸中毒管理中的应用

Terbutaline in the management of acute intrapartum fetal acidosis.

作者信息

Tejani N A, Verma U L, Chatterjee S, Mittelmann S

出版信息

J Reprod Med. 1983 Dec;28(12):857-61.

PMID:6663586
Abstract

A beta 2-mimetic agent, terbutaline, was used before full cervical dilatation in 10 of 18 cases of fetal distress evidenced by fetal scalp blood pH (FSB-pH) less than 7.25. A reduction in uterine activity with an improvement in the fetal heart rate trace was seen in all the cases. In addition, a significant improvement in FSB-pH, when compared with umbilical artery pH (p less than 0.05), was noted whereas there was no significant change in the untreated cases. An Apgar score of less than or equal to 6 at five minutes occurred in two of eight untreated patients but not in any treated patients.

摘要

在18例因胎儿头皮血pH值(FSB-pH)低于7.25而确诊为胎儿窘迫的病例中,有10例在宫颈完全扩张前使用了β2-拟交感神经药特布他林。所有病例均出现子宫活动减少,同时胎儿心率曲线改善。此外,与脐动脉pH值相比,FSB-pH有显著改善(p<0.05),而未治疗的病例则无显著变化。8例未治疗的患者中有2例在5分钟时Apgar评分小于或等于6分,但治疗的患者中无此情况。

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