Arias F
Am J Obstet Gynecol. 1978 May 1;131(1):39-43. doi: 10.1016/0002-9378(78)90471-4.
Terbutaline, a selective beta-2 adrenergic receptor stimulator, has been used to decrease myometrial activity and improve uteroplacental blood flow in 15 patients with acute intrapartum fetal distress. In all cases electronic monitoring gave evidence of partial or total fetal recovery after therapy. Thirteen of these patients were delivered by cesarean section and two were allowed to resume labor and deliver vaginally. In 10 cases the initial Apgar score was 7 or more and in all cases the score was 7 or more after 5 minutes of life. No significant maternal morbidity occurred as a consequence of the treatment. These results suggest that inhibition of uterine activity with terbutaline may be a valuable maneuver in the management of patients with severe intrapartum fetal distress.
特布他林是一种选择性β2肾上腺素能受体激动剂，已用于15例急性分娩期胎儿窘迫患者，以降低子宫肌层活动并改善子宫胎盘血流。在所有病例中，电子监测显示治疗后胎儿部分或完全恢复。其中13例患者行剖宫产分娩，2例继续分娩并经阴道分娩。10例患者出生时1分钟阿氏评分≥7分，所有病例出生后5分钟评分均≥7分。治疗未导致明显的母体并发症。这些结果表明，用特布他林抑制子宫活动可能是治疗严重分娩期胎儿窘迫患者的一种有效方法。
