在发展中国家停留的日本志愿者中甲型肝炎病毒感染的发生率。

Incidence of hepatitis A virus infection among Japanese volunteers staying in developing countries.

作者信息

Naruto H, Shimizu Y, Iwata K, Tanabe K

出版信息

Jpn J Exp Med. 1983 Apr;53(2):135-7.

Abstract

Incidence of hepatitis A virus infection was studied serologically in 260 adult males and females sent for volunteer service to developing countries from Japan. Among 225 initially seronegative subjects, 29 (12.9%) were seropositive to hepatitis A virus at their return from two year's overseas service. Seroconversion occurred in none of 39 subjects who received two doses or more of prophylactic administration of human immunoglobulin. There were clinical records of acute non-B hepatitis in 10 subjects among 29 who seroconverted to hepatitis A virus, while in 6 among 231 who did not seroconvert.

摘要

对从日本前往发展中国家志愿服务的260名成年男女进行了甲型肝炎病毒感染发生率的血清学研究。在225名最初血清学阴性的受试者中，29人（12.9%）在两年海外服务归来时甲型肝炎病毒血清学呈阳性。在接受两剂或更多剂量人免疫球蛋白预防性给药的39名受试者中，无一发生血清转化。在血清转化为甲型肝炎病毒的29名受试者中有10人有急性非B型肝炎的临床记录，而在未发生血清转化的231名受试者中有6人有此记录。