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[蜂毒超敏反应中蜂毒特异性IgG抗体的测定及特异性IgE抗体与总IgE的关系]

[Measurement of bee venom specific IgG antibody in bee venom hypersensitivity and the relation between the specific IgE antibody and total IgE].

作者信息

Goto A, Ohtani M

出版信息

Radioisotopes. 1983 Sep;32(9):404-10.

PMID:6665232
Abstract

Bee venom specific IgG antibodies for honeybee and common wasp were measured in normal control group, slightly bee injury group, heavy bee injury group and honeybee keeper's group. Relation among bee venom specific IgG antibody, bee venom specific IgE antibody and total IgE was analyzed. Normal control level of bee venom specific IgG antibody was measured under 60 U/ml. Bee venom specific IgG antibody in slightly bee injury group was higher than that in heavy bee injury group. Bee venom specific IgE antibody in slightly bee injury group was lower than that in heavy bee injury group. Bee venom specific IgE antibody in bee keeper's group was very high but bee venom specific IgG antibody was also high. From this results it seems that bee venom hypersensitivity can be prevented by high titer of bee venom specific IgG antibody even if bee venom specific IgE antibody is high titer.

摘要

在正常对照组、轻度蜜蜂蛰伤组、重度蜜蜂蛰伤组和养蜂人组中检测了针对蜜蜂和普通黄蜂的蜂毒特异性IgG抗体。分析了蜂毒特异性IgG抗体、蜂毒特异性IgE抗体和总IgE之间的关系。蜂毒特异性IgG抗体的正常对照水平测定为低于60 U/ml。轻度蜜蜂蛰伤组的蜂毒特异性IgG抗体高于重度蜜蜂蛰伤组。轻度蜜蜂蛰伤组的蜂毒特异性IgE抗体低于重度蜜蜂蛰伤组。养蜂人组的蜂毒特异性IgE抗体非常高,但蜂毒特异性IgG抗体也很高。从这些结果来看,即使蜂毒特异性IgE抗体是高滴度的,高滴度的蜂毒特异性IgG抗体似乎也可以预防蜂毒超敏反应。

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