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[复发性脑出血与淀粉样血管病]

[Recurrent cerebral hemorrhage and amyloid angiopathy].

作者信息

Julien J, Vital C, Lagueny A, Ferrer X, Vital A

出版信息

Rev Neurol (Paris). 1983;139(12):763-7.

PMID:6665391
Abstract

A patient with no previous relevant history presented with recurrent cerebral hemorrhages of which he died 4 years 5 months after the onset. On autopsy, an amyloid angiopathy was present and localised to the cerebrovascular system. Hemorrhages were associated with some small infarcts in the subcortical regions. The leptomeninges and the cortical arteries were mostly involved by an infiltration mainly in the adventitia and media. There were no senile plaques in the cortex. The amyloid deposit present in the senile plaques and in the vessel walls of the amyloid angiopathy could be the result of two distinct pathological processes.

摘要

一名既往无相关病史的患者出现反复脑出血,发病4年5个月后死亡。尸检发现存在淀粉样脑血管病,且局限于脑血管系统。出血与皮质下区域的一些小梗死灶有关。软脑膜和皮质动脉主要在外膜和中膜有浸润。皮质中没有老年斑。老年斑和淀粉样脑血管病血管壁中存在的淀粉样沉积物可能是两种不同病理过程的结果。

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