Lee S S, Stemmermann G N
Arch Pathol Lab Med. 1978 Jun;102(6):317-21.
All the cases of spontaneous intracerebral hemorrhage that were autopsied between 1965 and 1976 at at Kuakini Hospital, Hawaii, were analyzed to determine the frequency of coexistent cerebral congophilic angiopathy. Seven of 75 cases (9.3%) were confirmed to have deposition of amyloid in the intracerebral vessels by means of polarized light microscopy and electron microscopy. The cerebral congophilic angiopathy was found to have predilection for aged patients and women (ratio of 6:1). Diabetes mellitus, hypertension, atherosclerosis, systemic amyloidosis, and paraproteinemia did not appear to be associated with this change. There is, however, a strong correlation between classic as well as compact senile plaques and this vascular lesion.
对1965年至1976年间在夏威夷夸基尼医院进行尸检的所有自发性脑出血病例进行分析，以确定并存脑嗜刚果红血管病的频率。75例病例中有7例（9.3%）通过偏光显微镜和电子显微镜证实脑内血管有淀粉样物质沉积。发现脑嗜刚果红血管病好发于老年患者和女性（比例为6:1）。糖尿病、高血压、动脉粥样硬化、系统性淀粉样变性和副蛋白血症似乎与这种变化无关。然而，经典型和致密型老年斑与这种血管病变之间存在很强的相关性。
