Semiglazov V F, Rzhankov S V, Migmanova N Sh, Kremen' B V, Barash N Iu
Vopr Onkol. 1983;29(12):25-30.
The paper presents the data on 3359 cases of breast cancer treated at the Institute. A slight (4.7-7.6%) though significant increase in five-year survival was registered within 20 years (1955-1975). It had gone up to 64.7% by 1971-1975. A significant increase was observed in patients under 50 years who received an adjuvant postoperative chemotherapy (thiotepa and 5-fluorouracil). Mortality from distant metastases within the first 15 years after the beginning of therapy decreased from 89.5 to 68.8% and it was as low as 7.6% at later periods.
该论文展示了在该研究所治疗的3359例乳腺癌病例的数据。在20年（1955 - 1975年）期间，五年生存率虽有轻微（4.7 - 7.6%）但显著提高。到1971 - 1975年，已升至64.7%。在接受术后辅助化疗（噻替派和5 - 氟尿嘧啶）的50岁以下患者中观察到显著增加。治疗开始后的前15年内远处转移导致的死亡率从89.5%降至68.8%，后期低至7.6%。
