Sutherland A M
Arch Gynecol. 1983;234(2):95-101. doi: 10.1007/BF00207681.
Between 1st January, 1951 and 31st December, 1980, 704 women with proven tuberculosis of the genital tract were investigated. The previous obstetrical history, age incidence, presenting symptoms, and pelvic findings have been reviewed in 10-year periods. The incidence of previous pregnancies rose in successive periods and the average age increased. The main differences in the presenting symptoms were a lessening in the frequency of amenorrhoea and vaginal discharge and an increase in postmenopausal bleeding. The incidence of palpable adnexal masses decreased in successive 10-year periods. Short drug courses were mainly employed in the earlier years and longer courses in the later years. The drugs used initially were streptomycin, PAS and isoniazid, ethambutol and rifampicin being introduced later. The incidence of surgical treatment following failure of drug therapy was much higher in those who had received short drug courses than in those who had received longer ones.
在1951年1月1日至1980年12月31日期间,对704名经证实患有生殖道结核的女性进行了调查。对她们之前的产科病史、年龄发病率、出现的症状以及盆腔检查结果按10年时间段进行了回顾。在连续的时间段里,既往妊娠的发生率上升,平均年龄增加。出现的症状的主要差异在于闭经和阴道分泌物的频率降低,以及绝经后出血增加。在连续的10年时间段里,可触及的附件肿块的发生率下降。早期主要采用短疗程药物治疗,后期采用长疗程药物治疗。最初使用的药物是链霉素、对氨基水杨酸和异烟肼,后来引入了乙胺丁醇和利福平。药物治疗失败后进行手术治疗的发生率,接受短疗程药物治疗的患者比接受长疗程药物治疗的患者高得多。