Sutherland A M
J Obstet Gynaecol. 1997 Mar;17(2):119-22. doi: 10.1080/01443619750113618.
A study has been made of 711 patients with proved gynaecological tuberculosis investigated between 1 January 1951 and 31 December 1994. The main presenting symptoms in order of frequency were infertility, pelvic pain, excessive menstrual loss and amenorrhoea. The average age at first attendance was 31 years, only 16% of married women had been pregnant and palpable adnexal masses were found in 47%. Eight drug programmes were used, the best results being obtained with streptomycin, para-aminosalicyclic (PAS) acid and isoniazid or with rifampicin, ethambutol and isoniazid. Toxic drug reactions occurred in 114 patients, the drugs responsible in the majority being streptomycin and PAS. Where drug treatment failed, surgery under further drug cover was employed in 85 patients, with no deaths and no fistulae. After treatment, there were 95 pregnancies in 57 patients. In recent years there has been a rise in the incidence of tuberculosis in general in the Western world. Many factors play a part in this, by far the most important being the spread of AIDS.
对1951年1月1日至1994年12月31日期间确诊的711例妇科结核病患者进行了一项研究。主要出现症状按频率排序依次为不孕、盆腔疼痛、月经过多和闭经。首次就诊时的平均年龄为31岁，只有16%的已婚女性曾怀孕，47%的患者可触及附件肿块。使用了8种药物方案，使用链霉素、对氨基水杨酸（PAS）和异烟肼，或利福平、乙胺丁醇和异烟肼取得了最佳效果。114例患者出现药物毒性反应，大多数情况下导致反应的药物是链霉素和PAS。当药物治疗失败时，85例患者在进一步药物覆盖下接受了手术，无死亡病例，也无瘘管形成。治疗后，57例患者中有95次妊娠。近年来，西方世界结核病的总体发病率有所上升。许多因素导致了这种情况，其中最重要的是艾滋病的传播。
