Deiana L, Congiu A M, Arena N
Boll Soc Ital Biol Sper. 1983 Nov 30;59(11):1718-24.
A primary objective of the work described here was to determine the embryo-toxic effects induced by Nickel Sulfate upon the development of the Paracentrotus Lividus. Different concentrations of Nickel Sulfate have been dissolved in containers with not foul sea-water. The fecundation took place in the containers and verified by constant observations with a light microscope. The development of the Paracentrotus 1. was totally blocked at a concentration of 0.5 M.10(-2) of Nickel Sulfate, while an enormous development was observed at concentrations of 0.5 M.10(-3) and 0.5 M.10(-4). Finally, a concentration of 0.5 M.10(-5) caused a slow development. A normal development was observed only at a concentration of 0.5 M.10(-6). Our results support various hypotheses on the mechanism of action of the Nickel Sulfate as an inhibitor of the normal development.
本文所述工作的一个主要目标是确定硫酸镍对紫海胆发育产生的胚胎毒性作用。不同浓度的硫酸镍已溶解在未受污染的海水中的容器中。受精在这些容器中进行，并通过光学显微镜持续观察加以验证。紫海胆的发育在硫酸镍浓度为0.5M.10(-2)时完全受阻，而在浓度为0.5M.10(-3)和0.5M.10(-4)时观察到大量发育。最后，浓度为0.5M.10(-5)导致发育缓慢。仅在浓度为0.5M.10(-6)时观察到正常发育。我们的结果支持了关于硫酸镍作为正常发育抑制剂作用机制的各种假设。
