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[家兔脊髓血流量的测量:中央灰质血流量及二氧化碳反应性(作者译)]

[Measurement of spinal cord blood flow in rabbits: central gray matter flow and CO2 reactivity (author's transl)].

作者信息

Tamura A, Asano T, Sano K

出版信息

No To Shinkei. 1978 Apr;30(4):383-6.

PMID:666908
Abstract

Spinal cord blood flow (SCBF) was measured in 20 rabbits anesthetized with sodium pentobarbital. The platinum electrodes (0.3 mm in diameter) were inserted into the central gray matter of the thoracic spinal cord (Th8-10). In all animals, blood pressure and pAO2 remained constantly in the normal range. The pACO2 was changed by ventilation. Blood gases were checked both before and after each spinal cord blood flow measurement. The results are as follows. 1. Seventy-three percent of the clearances recorded from the gray matter were monoexponential and in the white matter almost all were monoexponential. 2. The mean values of gray matter SCBF of all animals was 38.3 +/- 1.85 ml/100 g/min (SE) at normo-capnea and the white matter was 19.5 +/- 1.33 ml/100 g/min. 3. An almost linear relationship exists between the pACO2 and SCBF. The values were 0.62 ml/100 g/min/torr in the gray matter and 0.38 ml/100 g/min/torr in the white matter.

摘要

在20只戊巴比妥钠麻醉的家兔身上测量脊髓血流量(SCBF)。将直径0.3毫米的铂电极插入胸段脊髓(Th8 - 10)的中央灰质。在所有动物中,血压和动脉血氧分压一直保持在正常范围内。通过通气改变动脉血二氧化碳分压(pACO2)。在每次测量脊髓血流量前后都检查血气。结果如下:1. 灰质记录的清除率中73%为单指数形式,白质中几乎全部为单指数形式。2. 在正常二氧化碳分压时,所有动物灰质脊髓血流量的平均值为38.3±1.85毫升/100克/分钟(标准误),白质为19.5±1.33毫升/100克/分钟。3. pACO2与脊髓血流量之间存在几乎线性的关系。灰质中的值为0.62毫升/100克/分钟/托,白质中为0.38毫升/100克/分钟/托。

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