Jouppila R, Jouppila P, Hollmén A, Kuikka J
Br J Anaesth. 1978 Jun;50(6):563-7. doi: 10.1093/bja/50.6.563.
Placental blood flow was measured during the first stage of normal labour using a xenon-133 clearance technique before and after segmental extradural analgesia. Analgesia was produced with 0.5% plain bupivacaine in eight patients and with 0.5% bupivacaine--adrenaline in 10 patients. Segmental extradural analgesia with a small dose (20 mg) of bupivacaine did not change placental blood flow significantly. The addition of adrenaline 20 microgram produced no effect.
在正常分娩第一产程中，使用氙 - 133清除技术在节段性硬膜外镇痛前后测量胎盘血流量。8例患者使用0.5%的普通布比卡因进行镇痛，10例患者使用0.5%布比卡因加肾上腺素进行镇痛。小剂量（20毫克）布比卡因的节段性硬膜外镇痛并未显著改变胎盘血流量。添加20微克肾上腺素也无影响。
