Völcker H E, Naumann G O
Br J Ophthalmol. 1978 Jun;62(6):408-13. doi: 10.1136/bjo.62.6.408.
Two completely separate malignant melanomas of the choroid occurred in 1 eye containing 2 additional uveal naevi. Review of the literature disclosed 7 further patients with unilateral multicentric malignant melanomas of the choroid and 11 bilateral multicentric malignant melanomas of the uvea. General aspects of multicentric primary neoplasia are discussed and an interpretation is attempted.
一只眼睛中出现了两个完全独立的脉络膜恶性黑色素瘤,该眼还另有两个葡萄膜痣。文献回顾发现,还有7例单侧脉络膜多中心恶性黑色素瘤患者以及11例双侧葡萄膜多中心恶性黑色素瘤患者。本文讨论了多中心原发性肿瘤的一般情况并尝试进行解读。