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脉络膜多中心原发性恶性黑色素瘤：一只眼睛中有两个独立的脉络膜恶性黑色素瘤和两个葡萄膜痣。

Multicentric primary malignant melanomas of the choroid: two separate malignant melanomas of the choroid and two uveal naevi in one eye.

作者信息

Völcker H E, Naumann G O

出版信息

Br J Ophthalmol. 1978 Jun;62(6):408-13. doi: 10.1136/bjo.62.6.408.

DOI:10.1136/bjo.62.6.408
PMID:666990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1043244/
Abstract

Two completely separate malignant melanomas of the choroid occurred in 1 eye containing 2 additional uveal naevi. Review of the literature disclosed 7 further patients with unilateral multicentric malignant melanomas of the choroid and 11 bilateral multicentric malignant melanomas of the uvea. General aspects of multicentric primary neoplasia are discussed and an interpretation is attempted.

摘要

一只眼睛中出现了两个完全独立的脉络膜恶性黑色素瘤，该眼还另有两个葡萄膜痣。文献回顾发现，还有7例单侧脉络膜多中心恶性黑色素瘤患者以及11例双侧葡萄膜多中心恶性黑色素瘤患者。本文讨论了多中心原发性肿瘤的一般情况并尝试进行解读。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/8fe4d34e12c6/brjopthal00222-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/20b84a464be4/brjopthal00222-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/6e75525c8738/brjopthal00222-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/1b398e15f0d0/brjopthal00222-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/a3ad226dbc8f/brjopthal00222-0071-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/8fe4d34e12c6/brjopthal00222-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/20b84a464be4/brjopthal00222-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/6e75525c8738/brjopthal00222-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/1b398e15f0d0/brjopthal00222-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/a3ad226dbc8f/brjopthal00222-0071-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee7/1043244/8fe4d34e12c6/brjopthal00222-0072-a.jpg

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1
Multicentric primary malignant melanomas of the choroid: two separate malignant melanomas of the choroid and two uveal naevi in one eye.脉络膜多中心原发性恶性黑色素瘤：一只眼睛中有两个独立的脉络膜恶性黑色素瘤和两个葡萄膜痣。
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Multifocal Primary Uveal Melanoma: Clinical and Molecular Characteristics.多灶性原发性葡萄膜黑色素瘤：临床和分子特征
Ocul Oncol Pathol. 2019 Jan;5(1):8-12. doi: 10.1159/000487891. Epub 2018 Apr 27.
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Two Uveal Melanomas in One Eye: A Choroidal Nevus Giving Rise to a Melanoma in an Eye with a Separate Large Choroidal Melanoma.

本文引用的文献

1
Simultaneous bilateral primary ocular malignant melanoma; report of a case.双眼同时发生原发性眼恶性黑色素瘤；病例报告
Trans Am Ophthalmol Soc. 1949;47:80-92.
2
[BILATERAL MALIGNANT MELANOBLASTOMA OF THE CHOROID].[脉络膜双侧恶性成黑素细胞瘤]
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MULTIPLE MALIGNANT MELANOMA OF THE CHOROID.脉络膜多发性恶性黑色素瘤
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Multiple malignant melanomata of the uveal tract in one eye.一只眼睛葡萄膜的多发性恶性黑色素瘤。
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Primary malignant melanoma of the skin metastatic to the eye and orbit. Report of ten cases and review of the literature.
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Histogenesis of malignant melanomas of the uvea. II. Relationship of uveal nevi to malignant melanomas.
Cancer. 1967 Apr;20(4):493-507. doi: 10.1002/1097-0142(1967)20:4<493::aid-cncr2820200406>3.0.co;2-u.
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Histogenesis of malignant melanomas of the uvea. I. Histopathologic characteristics of nevi of the choroid and ciliary body.葡萄膜恶性黑色素瘤的组织发生。I. 脉络膜和睫状体痣的组织病理学特征。
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Heredity and intraocular malignant melanoma. Study of two families and review of forty-five cases.遗传与眼内恶性黑色素瘤。两个家族的研究及45例病例回顾。
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