Bacin F, Kemeny J L, D'Hermies F, Rozan R, Decroix P, Dalens H, Kalifa C
Service d'Ophtalmologie, C.H.R.U., Hôpital Gabriel Montpied, Clermont-Ferrand.
J Fr Ophtalmol. 1993;16(3):184-90.
A sixteen-year-old white girl with peripheral neurofibromatosis (NF1), who had been treated for a glioma of the optic nerves and chiasma developed a choroidal mass in her only functional eye. After a transchoroïdal biopsy, the pathologic examination disclosed a choroïdal melanoma of epithelioid cell type, using morphological criteria as well as an immunohistochemical study. After treatment with a ruthenium plaque, the tumor completely regressed over 4 months. According to the data of the literature, neurofibromatosis seems to predispose to the development of uveal melanomas.
一名患有外周神经纤维瘤病（NF1）的16岁白人女孩，曾接受过视神经和视交叉胶质瘤治疗，其仅有的一只功能眼中出现了脉络膜肿物。经脉络膜活检后，病理检查依据形态学标准及免疫组织化学研究，发现为上皮样细胞型脉络膜黑色素瘤。在用钌板治疗后，肿瘤在4个月内完全消退。根据文献数据，神经纤维瘤病似乎易诱发葡萄膜黑色素瘤的发生。
