通过大规模筛查发现的宫颈癌的治疗。

Therapy for cervical cancer detected by mass screening.

作者信息

Yajima A, Sato S, Higashiiwai H, Mori T, Wada Y, Yamauchi R, Uehara S, Suzuki M

出版信息

Tohoku J Exp Med. 1983 Dec;141(4):451-6. doi: 10.1620/tjem.141.451.

DOI:10.1620/tjem.141.451

Abstract

Over a 19 year period since 1962, 972 cases of cervical cancer have been detected by mass screening in Miyagi Prefecture, a detection rate of 0.11%. Among these cases, 551 (56.7%) were cases of carcinoma in situ. In contrast, cervical cancers detected by means of private screening gave a detection rate of 0.39% (889 cases), among which there were 611 cases of invasive carcinoma (68.7%). Among the 421 cases of invasive carcinoma detected by mass screening, 352 were Stage I, 52 were Stage II, 14 were Stage III and 1 was Stage IV. Moreover, 178 of the 352 Stage I cases were Stage Ia. The 5 year survival rate for the cervical cancer patients detected by mass screening was 97.8% for Stage 0, 92.9% for Stage I, 75% for Stage II, 45.5% for Stage III and 0% for Stage IV. The 5-year survival rate for invasive carcinoma was 88.7%. Twenty-five deaths due to recurrence of the cancer were found, but all such cases were invasive carcinomas. There were no mortalities due to recurrence of carcinoma in situ among such cases detected by mass screening.

摘要

自1962年以来的19年间，宫城县通过大规模筛查共检测出972例宫颈癌病例，检出率为0.11%。其中，551例（56.7%）为原位癌病例。相比之下，通过个人筛查检测出的宫颈癌病例检出率为0.39%（889例），其中有611例浸润癌（68.7%）。在通过大规模筛查检测出的421例浸润癌病例中，352例为I期，52例为II期，14例为III期，1例为IV期。此外，352例I期病例中有178例为Ia期。通过大规模筛查检测出的宫颈癌患者的5年生存率，0期为97.8%，I期为92.9%，II期为75%，III期为45.5%，IV期为0%。浸润癌的5年生存率为88.7%。发现有25例因癌症复发死亡，但所有这些病例均为浸润癌。在通过大规模筛查检测出的原位癌病例中，没有因原位癌复发导致的死亡病例。