Morita T, Suzuki T, Kondo S, Tsuchida S
Tohoku J Exp Med. 1983 Dec;141(4):489-90. doi: 10.1620/tjem.141.489.
Experiments in vitro were performed to compare effects of noradrenaline and acetylcholine on the pyeloureter, both of which activate ureteral peristalsis. Noradrenaline elevated the baseline renal pressure to accelerate the ureteral peristalic pace in a ratio of 1:1 with the pacemaker discharge at the pelvicalyceal border (PC-border). Acetylcholine also accelerated the ureteral pace for a short time, as compared with the effect of noradrenaline. The baseline renal pelvic pressure dropped after administration of acetylcholine. Noradrenaline a little quickened the rhythm of the pacemaker contraction at the PC-border, and acetylcholine also quickened the pacemaker rhythm. These data suggest that noradrenaline and acetylcholine, which both activate pelviureteral peristalsis, exert different effects on pelvic pressure.
进行了体外实验以比较去甲肾上腺素和乙酰胆碱对肾盂输尿管的影响，这两种物质均可激活输尿管蠕动。去甲肾上腺素升高了基线肾压力，以与肾盂输尿管交界处（PC交界处）起搏器放电1:1的比例加速输尿管蠕动速度。与去甲肾上腺素的作用相比，乙酰胆碱也在短时间内加速了输尿管蠕动速度。给予乙酰胆碱后，基线肾盂压力下降。去甲肾上腺素略微加快了PC交界处起搏器收缩的节律，乙酰胆碱也加快了起搏器节律。这些数据表明，均可激活肾盂输尿管蠕动的去甲肾上腺素和乙酰胆碱对肾盂压力产生不同影响。
